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Masataka Kuwana Selected Research

Epoprostenol (Prostacyclin)

4/2023SATISFY-JP, a phase II multicenter open-label study on Satralizumab, an anti-IL-6 receptor antibody, use for the treatment of pulmonary arterial hypertension in patients with an immune-responsive-phenotype: Study protocol.
1/2015Rapid initiation of intravenous epoprostenol infusion is the favored option in patients with advanced pulmonary arterial hypertension.
5/2014IgG4-related disease in pulmonary arterial hypertension on long-term epoprostenol treatment.
11/2013Intravenous epoprostenol treatment of patients with connective tissue disease and pulmonary arterial hypertension at a single center.

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Masataka Kuwana Research Topics

Disease

68Interstitial Lung Diseases (Interstitial Lung Disease)
05/2024 - 06/2004
57Systemic Scleroderma (Systemic Sclerosis)
12/2023 - 10/2002
44Dermatomyositis (Dermatopolymyositis)
12/2023 - 06/2004
41Myositis (Idiopathic Inflammatory Myopathies)
01/2024 - 08/2007
35Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune)
01/2024 - 04/2002
26Melanoma (Melanoma, Malignant)
12/2023 - 07/2009
22Autoimmune Diseases (Autoimmune Disease)
05/2024 - 04/2003
19Rheumatoid Arthritis
07/2023 - 01/2006
17Pulmonary Arterial Hypertension
05/2024 - 01/2010
16Connective Tissue Diseases (Connective Tissue Disease)
11/2020 - 12/2003
14Fibrosis (Cirrhosis)
03/2024 - 06/2003
13COVID-19
05/2024 - 01/2022
13Systemic Lupus Erythematosus (Libman-Sacks Disease)
04/2024 - 08/2002
13Polymyositis
05/2023 - 10/2005
11Infections
11/2023 - 02/2005
11Thrombocytopenia (Thrombopenia)
11/2023 - 08/2002
10Diffuse Scleroderma (Progressive Systemic Sclerosis)
03/2024 - 03/2007
9Neoplasms (Cancer)
07/2023 - 01/2010
9Amyopathic dermatomyositis
01/2022 - 05/2005
8Disease Progression
04/2024 - 01/2010
8Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome)
01/2018 - 04/2002
7Idiopathic Pulmonary Fibrosis
04/2024 - 05/2005
6Muscular Diseases (Myopathy)
05/2023 - 01/2009
6Myasthenia Gravis
08/2011 - 04/2003
5Pulmonary Fibrosis (Fibrosing Alveolitis)
05/2024 - 07/2009
5Simian Acquired Immunodeficiency Syndrome
05/2024 - 12/2022
5Inclusion Body Myositis
01/2024 - 01/2017
5Rheumatic Diseases (Rheumatism)
12/2023 - 03/2021
5Aplastic Anemia (Anemia, Hypoplastic)
11/2023 - 09/2005
5Hemorrhage
01/2023 - 06/2004
5Muscle Weakness
05/2022 - 09/2014
5Thrombosis (Thrombus)
10/2014 - 01/2003
5Thymoma (Thymic Carcinoma)
05/2013 - 12/2003
4Pulmonary Hypertension
05/2024 - 07/2015
4digital ulcers
12/2023 - 02/2015
4Behcet Syndrome (Behcet's Syndrome)
06/2023 - 11/2004
4Mixed Connective Tissue Disease (MCTD)
01/2021 - 10/2012
4Atrophy
01/2017 - 12/2005
4Inflammation (Inflammations)
01/2015 - 01/2009
4Pemphigus (Pemphigus Vulgaris)
09/2011 - 02/2007
3Dyspnea (Shortness of Breath)
04/2024 - 01/2019
3Fatigue
04/2024 - 01/2023
3Necrosis
04/2023 - 03/2004
3Takayasu Arteritis (Arteritis, Takayasu's)
01/2023 - 12/2018
3Pain (Aches)
01/2023 - 06/2014
3Diarrhea
03/2021 - 01/2019
3Purpura
01/2020 - 08/2003

Drug/Important Bio-Agent (IBA)

80AutoantibodiesIBA
12/2023 - 04/2002
46AntibodiesIBA
01/2024 - 08/2002
30Inosine Triphosphate (ITP)IBA
11/2023 - 08/2002
19Amino Acyl-tRNA Synthetases (Aminoacyl-tRNA Synthetase)IBA
04/2023 - 05/2007
18EnzymesIBA
03/2024 - 08/2002
16Biomarkers (Surrogate Marker)IBA
03/2024 - 05/2009
13Proteins (Proteins, Gene)FDA Link
12/2023 - 12/2003
12VaccinesIBA
05/2024 - 01/2022
12nintedanibIBA
04/2024 - 01/2019
12ImmunosorbentsIBA
03/2024 - 08/2002
12tocilizumab (atlizumab)FDA Link
07/2023 - 01/2010
12Immunoglobulin G (IgG)IBA
01/2016 - 01/2003
11Adrenal Cortex Hormones (Corticosteroids)IBA
12/2023 - 12/2003
10COVID-19 VaccinesIBA
05/2024 - 01/2023
9AntigensIBA
11/2014 - 08/2002
8Signal Recognition ParticleIBA
07/2017 - 09/2005
7Ligases (Synthetase)IBA
01/2024 - 06/2004
7CytokinesIBA
12/2023 - 03/2004
7Interleukin-6 (Interleukin 6)IBA
04/2023 - 01/2010
7Cyclophosphamide (Cytoxan)FDA LinkGeneric
01/2022 - 12/2010
7Ferritins (Ferritin)IBA
06/2018 - 04/2011
6Thrombopoietin (c-mpl Ligand)IBA
11/2023 - 08/2002
6Monoclonal AntibodiesIBA
06/2023 - 01/2003
6Intravenous Immunoglobulins (IVIG)FDA Link
05/2023 - 04/2006
6Peptides (Polypeptides)IBA
03/2019 - 04/2003
5RNA (Ribonucleic Acid)IBA
12/2023 - 09/2014
5Immunosuppressive Agents (Immunosuppressants)IBA
05/2023 - 10/2003
5Mi-2 antibodiesIBA
04/2023 - 04/2011
5transcriptional intermediary factor 1IBA
01/2020 - 09/2012
5beta-cyclodextrin tetradecasulfate (CTDS)IBA
12/2016 - 05/2005
4Methotrexate (Mexate)FDA LinkGeneric
03/2024 - 11/2013
4GlucocorticoidsIBA
01/2024 - 01/2015
4Epoprostenol (Prostacyclin)FDA LinkGeneric
04/2023 - 11/2013
4Glycoproteins (Glycoprotein)IBA
11/2022 - 01/2003
4Antineutrophil Cytoplasmic Antibodies (ANCA)IBA
01/2021 - 06/2004
4AutoantigensIBA
09/2011 - 06/2003
4beta 2-Glycoprotein I (Apolipoprotein H)IBA
12/2007 - 04/2002
4Cholinergic ReceptorsIBA
08/2007 - 04/2003
3Indicators and Reagents (Reagents)IBA
04/2024 - 11/2013
3LigandsIBA
03/2024 - 08/2003
3ChemokinesIBA
03/2024 - 11/2013
3riociguatIBA
03/2024 - 01/2020
3Antiviral Agents (Antivirals)IBA
12/2023 - 01/2022
3C-Reactive ProteinIBA
12/2023 - 01/2022
3Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
11/2023 - 11/2006
3Vasodilator Agents (Vasodilators)IBA
04/2023 - 01/2018
3Antirheumatic Agents (DMARD)IBA
04/2023 - 09/2017
3Immunoglobulin M (IgM)IBA
05/2022 - 04/2006
3Calcineurin InhibitorsIBA
01/2022 - 04/2018
3Rituximab (Mabthera)FDA Link
01/2021 - 11/2004
3Pulmonary Surfactant-Associated Protein D (Surfactant Protein D)IBA
01/2020 - 06/2018

Therapy/Procedure

30Therapeutics
05/2024 - 10/2003
3Immunomodulation
10/2023 - 11/2009